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Advances in Protein Molecular and Structural Biology Methods
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Advances in Protein Molecular and Structural Biology Methods offers a complete overview of the latest tools and methods applicable to the study of proteins at the molecular and structural level. This book begins with sections exploring tools to optimize recombinant protein expression and biophysical techniques such as fluorescence spectroscopy, NMR, mass spectrometry, cryo-electron microscopy and x-ray crystallography. The book then moves towards computational approaches, considering structural bioinformatics, molecular dynamics simulations, and deep machine learning technologies. It also includes a section dedicated to methods applied to intrinsically disordered proteins (IDPs), followed by chapters on protein interaction networks, protein function, and protein design and engineering. This book provides researchers with an extensive toolkit of methods and techniques to draw from when conducting their own experimental work, taking them from foundational concepts to practical application. Presents a thorough overview of the latest and emerging methods and technologies for protein study Explores biophysical techniques, including nuclear magnetic resonance, x-ray crystallography, and cryo-electron microscopy Includes computational and machine learning methods Features a section dedicated to tools and techniques specific to studying intrinsically disordered proteins
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