Cancer Biomarkers: Clinical Aspects and Laboratory Determination

Cancer Biomarkers: Clinical Aspects and Laboratory Determination meets the urgent need to develop novel cancer biomarker tests with high sensitivity and specificity for early diagnosis, staging and monitoring of disease progression and response to therapy to reduce cancer morbidity and mortality. It provides a comprehensive overview of current biomarkers for cancer detection, monitoring and recurrence focusing on emerging technologies and the impact on the field as well as a discussion of selected biomarkers currently used in clinical practice, highlighting the contribution of biomarkers in personalizing treatment for cancer patients. The content will highlight current laboratory tests used in the management of adult and pediatric cancer patients followed by an in-depth discussion of traditional and non-traditional biomarkers and investigation into the role of Circulating Tumor Cells and circulating tumor DNA as biomarkers in cancer management as well as cytokines in monitoring response to CAR T therapies. This title is the perfect reference for clinical pathologists; laboratory scientists; medical technologists; physicians specializing in oncology, internal medicine, family practice and transplant medicine; resident physicians; medical students; nurse practitioners, and clinical chemists. Provides insight into the overall complexity that the cancer patient presents and how laboratory tests are used in the management of care Discusses current and new technologies as they are applicable to cancer biomarkers evaluation including the use of non-traditional specimens including saliva, fluids and uterine lavage Reviews current trends in Liquid biopsy and cancer biomarkers Provides a roadmap of bringing new technologies and markers from the bench to the bedside in the quest for finding the ideal tumor marker