Cryo-EM Methods and Management

Cryo-EM Methods and Management provides a detailed introduction to the latest advances of cryo-EM, from technical innovations to the logistical challenges of maintaining a modern cryo-EM facility. The book consists of four parts, beginning with an overview of cryo-EM. It then moves on to discuss Cryo-EM workflows, with chapters focusing on sample handling and preparation, data collection and hardware, and data procession and visualization. The third part centers on aspects of cryo-EM infrastructure and community building, considering facility set-up and management, monitoring facility performance, instrumentation monitoring , data sharing and standards, and training and development standards. The book then closes with a section looking towards future prospects for cryo-EM. This is an ideal reference for cryo-EM facility and lab managers, providing guidance to the often-overlooked aspect of facility building and management. Additionally researchers working with cryo-EM across molecular biology, structural biology, cell biology and biochemistry will benefit from this book.

• Offers a comprehensive overview of the latest advances and methodologies in cryo-EM
• Includes guidance on sample preparation, data collection and data processing
• Shares insights into setting up, maintaining, and managing a cryo-EM facility
• Considers future developments in the field