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This second edition provides a cutting-edge, problem-orientated approach to the management of clinical problems in endocrinology. Highlights include neuroendocrine disease, pituitary radiotherapy and surgery, changes in diagnostic imaging and the increasing use of positron emission tomography, and mechanistic and genomic advances. The book also discusses the significance of aryl hydrocarbon receptor-interacting protein mutations, neuroendocrine tumors, the endocrinology of aging, and includes protocols for pituitary function testing. With complete updates of existing chapters, the second edition also presents new research data, diagnostic techniques, treatment options, and safety concerns related to existing therapies.