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Expression and purification of recombinant human interferon

Name: Expression and purification of recombinant human interferon
Brand: LAP LAMBERT Academic Publishing
SKU: 41447521
Price: 752 CZK
Availability: InStock
Author: Parasuraman Aiya Subramani
ISBN: 9786205491430

Parasuraman Aiya Subramani

Venkata Ramireddy Narala

Jazyk

Angličtina

Kniha Brožovaná

Libristo kód: 41447521

Nakladatelství LAP LAMBERT Academic Publishing, srpen 2022

Interferons, a family of cytokines, are released by cells in response to infection and inflammation.... Celý popis

Libristo kód: 41447521

75 b

752 Kč

Skladem u dodavatele Odesíláme za 8-11 dnů

Až 30 dní na vrácení zboží

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Interferons, a family of cytokines, are released by cells in response to infection and inflammation. Human interferons play a critical role in the immune system and have been licensed as antiviral and anticancer medicines. Human recombinant proteins have been created for several decades using a variety of host systems, including prokaryotes, yeast, and mammalian cells. Three distinct types of human interferon (IFN) genes have been cloned and produced in bacterial hosts for large-scale synthesis (IFN , beta, and Gamma). Increased interest in the purification and manufacture of high purity IFNs has been fueled by the growing therapeutic applications of human IFNs. This review discusses current advances in the production of recombinant human interferons using the E. coli expression system, as well as comparative purification strategies for increasing yields and biological activity.