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This book covers the immunological and clinical aspects of central and peripheral nervous system inflammatory diseases characterized by myelin damage. Leading scientists in the field have summarized in short reviews the state of the art of neuroimmunology, with particular emphasis on basic aspects of the regulation of immune responses during demyelinating disorders. The volume will be helpful to neuroimmunologists, but also to clinicians which will find a clear and concise understanding of the main features of neuroinflammatory disease.