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The pourpose of this work, based on my PhD thesis, was to develop a prototype of a homogeneous high throughput screening (HTS) for the identification of novel integrin antagonists. HTS is an extremely current topic in pharmacological research in order to withstand the necessity to provide a biological identity, in a reasonable time, to the ever increasing myriad of novel compounds obtained by Combinatorial Chemistry. I hope that the manuscript hereby presented could be a useful tool to other scientists who approach HTS for the first time and would like to develop their own original method.
Ahoj! Jsem Libroamiko, tvůj knižní rádce.
Jak ti můžu pomoct?