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This book is opening a new page and new look up at the stress response in surgical patients. Working on the mystic theory of glyco-regylation in surgical patients, the author has elaborated all the possible parts from this puzzle. Possibility to make some influence to get better glycometabolic function in patients who have energy input preoperatively is opening a new window in the anesthesiological approach to stress response. [Prof. Z. Nikolova] The actuality of the problem insulin resistance, glycemic, hormonal and insulin changes in surgical patients is small but essential angle for surgery patients. Revealing the secrets of glycol-metabolism in such simple manner is real rarity that makes this research applicative value enormous. It is time for clinicians to start thinking that the glicoregulation in surgical patients is the key feature for better patients outcome. [Prof. T. Milenkovic]