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Molecular Diagnostics
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"Molecular Diagnostics" covers current molecular biological techniques used to identify the underlying molecular defects in inherited disease. Although an increasing number of laboratories, both academic and private are moving in that direction, there are only a few books in the existing literature, and they deal only partly with diagnosis at the molecular level. Each chapter includes the principle and a brief description of the technique, followed by examples from the authors' own expertise. Contributors are well-known experts in their field, and derive from a variety of disciplines, to ensure breadth and depth of coverage. This book: examines widely used molecular biology techniques to screen for genetic defects causing inherited disorders; includes state-of-the-art techniques for the detection of the underlying genetic heterogeneity leading to inherited disorders; identification of genetically modified organisms (GMO's); forensic analysis and every-day issues in a diagnostic laboratory; and discusses ethics, genetic counselling and quality management.
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