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In this issue of Anesthesiology Clinics, guest editors Drs. Zdravka Zafirova and Richard D. Urman bring their considerable expertise to the topic of Preoperative Patient Evaluation. Top experts in the field discuss this important opportunity to identify co-morbidities that may lead to patient complications during the anaesthetic, surgical, or post-operative period, including anticoagulation preop management and regional anesthesia recent updates/guidelines; marijuana use and vaping; enhanced recovery pathways: preoperative considerations in children; management of preoperative anemia; and more.