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Dental caries is as an infectious microbiologic disease of the teeth that results in localized dissolution and destruction of the calcified tissues. Dental caries is a significant disease that affects children worldwide. Topical fluorides may be a valuable measure to arrest caries lesions because fluorides used in various forms have proven to be effective in dental caries prevention. Fluoride therapies are one of the most commonly used, evidence-based effective strategies for the prevention and management of dental caries. Several silver preparations, including silver nitrate, diamine silver fluoride, and stannous fluoride, have been used to prevent or arrest open carious lesions, particularly in the primary dentition. Silver salts can provide a pronounced antimicrobial action and have a long history of use in medicine and dentistry. Hence, the combined effects of silver and fluorides have been hypothesized to have the ability to halt caries progression and prevent the development of new caries simultaneously.
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