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The Psychedelic Brain: A Biobehavioral Evolutionary Approach to Psychedelics provides an up to date volume on the diverse effects that psychedelics have on the brain, experience, cognition, emotions, and treatment-resistant diseases. This volume provides biological and behavioral understandings of the significance of psychedelics across human evolution and their traditional and contemporary uses as therapies. The research presented offers interdisciplinary perspectives from neuropharmacology, clinical science, cross-cultural studies, and phenomenological research to provide readers with both classic and cutting-edge findings and a paradigmatic framework for future research into their mechanisms and applications.