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This book reviews the most recent developments in the patho-§physiology and therapy of ventilatory failure. It contains§contributions by twenty-five internationally recognized aut-§horities on respiratory muscle function and investigators§actively contributing to our knowledge of the cause, diagno-§sis and therapy of ventilatory failure. Of particular inter-§estare the descriptions of new modalities of partial and§complete ventilatory assistance as well as new knowledge re-§garding ventilatory control and fatigue during stressful§breathing. The reader will find here a state-of-the-art re-§view of the latest research and practical applications in§this most critical area of intensive care medicine.