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In this pioneering book, neuroscientist John T. Cacioppo unveils his groundbreaking research on the startling effects of loneliness: a sense of isolation or social rejection disrupts not only our thinking abilities and will-power but also our immune systems and can be as damaging as obesity or smoking. A blend of biological and social science, "Loneliness" demonstrates that, as individuals and as a society, we have everything to gain and everything to lose, in how well or how poorly we manage our need for social bonds.